Reports

Enzymatic Synthesis of Tri- and Tetranucleotides of Defined Sequence

Science  30 Apr 1965:
Vol. 148, Issue 3670, pp. 632-634
DOI: 10.1126/science.148.3670.632

Abstract

Conditions have been found under which polynucleotide phosphorylase adds only a few nucleotide residues to the 3' end of a dinucleotide primer. Pure tri- and tetranucleotides can be isolated from reaction mixtures in high yield.

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