Respiratory and Electrical Responses to Light Stimulation in the Retina of the Frog

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Science  30 Apr 1965:
Vol. 148, Issue 3670, pp. 648-651
DOI: 10.1126/science.148.3670.648


Isolated retinas from frogs' eyes were preserved in a circulating medium; transretinal electrical potential and ultraviolet absorbancy were monitored. In response to visible stimulation, changes in absorbancy were observed which correlate with the c-wave of the electroretinogram. They are tentatively identified as cyclic oxidations of pyridine nucleotides reflecting the energy expenditure associated with evoked neuronal activity.