Cellular Segregation and Heterocytic Dominance in Hydra

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Science  21 May 1965:
Vol. 148, Issue 3673, pp. 1105-1107
DOI: 10.1126/science.148.3673.1105


Hydra heterocytes—that is, hydra containing cells from both normal and mutant animals, were used for studying some developmental properties of mixed cell populations. Cells which initially had originated from a nonbudding mutant, and which subsequently became part of a heterocyte of normal appearance, were able to proliferate, to segregate, to come off as buds, and to express their phenotype in those buds. Furthermore, the heterocytes underwent a transformation in which the mutant phenotype eventually became dominant in all instances.