Electron Spin Resonance Spectroscopy: Application to Proof of Structure of Organic Ketones

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Science  28 May 1965:
Vol. 148, Issue 3674, pp. 1217-1218
DOI: 10.1126/science.148.3674.1217


Many ketones containing an α-methylene group can be converted to α-diketone radical anions in dimethyl sulfoxide solution. The resulting radical anions can usually be unambiguously identified by electron spin resonance spectroscopy, and the structure of the starting ketone may be deduced, often without reference to model compounds. The technique is also applicable to α-diketones, α-bromoketones, and α-hydroxyketones.