Nucleotide Synthesis under Possible Primitive Earth Conditions

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Science  28 May 1965:
Vol. 148, Issue 3674, pp. 1221-1223
DOI: 10.1126/science.148.3674.1221


The nucleosides adenosine, guanosine, cytidine, uridine, and thymidine were each heated with inorganic phosphate. Nucleoside monophosphates were formed in appreciable yield. This result has a bearing on the hypothesis of chemical evolution.