Radiolysis of Thymine in Aqueous Solutions: Change in Site of Attack with Change in pH

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Science  28 May 1965:
Vol. 148, Issue 3674, pp. 1234-1235
DOI: 10.1126/science.148.3674.1234


In the radiolysis of thymine in neutral air-saturated solutions the principal site of attack is at the 5,6 double bond; in strongly alkaline solutions the attack shifts to the 5-methyl group. The shift correlates well with a model based on two changes in the reaction path as the pH is increased.