Neurons of Insects: RNA Changes during Injury and Regeneration

See allHide authors and affiliations

Science  28 May 1965:
Vol. 148, Issue 3674, pp. 1237-1239
DOI: 10.1126/science.148.3674.1237


A dense concentration of RNA appears in the perinuclear cytoplasm of nerve cell bodies in the third thoracic ganglion of the cockroach within 12 hours after their axons are cut. The basiphilic material of the perinuclear ring reaches maximum development 2 to 3 days after axon injury and returns to normal at about 15 days. Ribonuclease removes the basiphilic material, indicating that it is RNA. The perinuclear ring of RNA provides a marker for linking an individual central nerve cell body to a particular peripheral axon and the muscle it innervates.