Glutamic-Oxaloacetic Transaminases in Reticulocytes and Erythrocytes

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Science  09 Jul 1965:
Vol. 149, Issue 3680, pp. 195-197
DOI: 10.1126/science.149.3680.195


In rabbits, mature erythrocytes contain only the anionic isozyme of glutamic-oxaloacetic transaminase. Reticulocytosis induced by massive bleeding or by treatment with acetylphenylhydrazine is characterized by a five- to sixfold increase in red-cell transaminase and the appearance of a cationic transaminase isozyme that apparently resides in the mitochondrial fraction of reticulocytes.