Reports

Interferon-Like Virus-Inhibitor Induced in Human Leukocytes by Phytohemagglutinin

Science  16 Jul 1965:
Vol. 149, Issue 3681, pp. 310-311
DOI: 10.1126/science.149.3681.310

Abstract

Phytohemagglutinin, an extract of the kidney bean, Phaseolus vulgaris, induces in human leukocyte cultures an inhibitor of the cytopathic effects of Sindbis virus. The physicochemical and biological properties of this virus-inhibitor are similar to those of interferon induced by Newcastle disease virus, except for an instability at pH 2 and 10 and at 56°C.

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