Cycasin: Radiomimetic Effect

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Science  30 Jul 1965:
Vol. 149, Issue 3683, pp. 541-542
DOI: 10.1126/science.149.3683.541


Cycasin, methylazoxy-methanol-β-glucoside, a carcinogenic compound that occurs naturally in cycad plants, induces chromosome aberrations in the root-tip cells of Allium cepa. Germination and growth in an aqueous solution of cycasin at a concentration of only 3 percent of that found in Cycas circinalis induced as many aberrations in chromosomes as did about 200 roentgens of gamma irradiation.