Progesterone: Biosynthesis from Pregnenolone in Holarrhena floribunda

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Science  06 Aug 1965:
Vol. 149, Issue 3684, pp. 652-653
DOI: 10.1126/science.149.3684.652


After administration of pregnenolone-4-C14 to Holarrhena floribunda leaves, radioactive progesterone was isolated and purified to constant specific activity by chromatography, conversion to a derivative, and recrystallization. The result suggests that the biogenetic sequence leading to progesterone is the same in plants as in animals.