Kidney Homografts: Uptake of Fluorochrome-Labeled Tissue Extracts byLymph Node Cells

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Science  13 Aug 1965:
Vol. 149, Issue 3685, pp. 753
DOI: 10.1126/science.149.3685.753


Regional lymph node cells of mongrel dogs which received kidney homografts after bilateral nephrecto-my take up fluorescein-isothiocyanate-labeled extracts of kidney tissue and of peripheral blood leukocytes. These fluorochrome-tissue conjugates were not taken up by cells from lymph nodes excisedfrom the experimental dogs at the time of transplantation or from normal dogs.