Crown-Gall Tumorigenesis: Effect of Temperature on Wound Healing and Conditioning

Science  20 Aug 1965:
Vol. 149, Issue 3686, pp. 865-867
DOI: 10.1126/science.149.3686.865-a


Temperatures which inhibit crown-gall tumorigenesis in Kalanchoé daigremontiana plants also accelerate the rate of wound healing and the rate at which cells in the wound area become competent to react to the tumorigenic stimulus. The concept that the "tumor-inducing principle" is thermolabile and of high molecular weight may be invalid since it is based in part on the lack of effect of temperature on wound healing and conditioning. The rate of division of host cells may determine the success of crown-gall tumorigenesis.