Tension Gradients Accompanying Accelerated Oxygen Transport in a Membrane

Science  20 Aug 1965:
Vol. 149, Issue 3686, pp. 876-877
DOI: 10.1126/science.149.3686.876


Facilitated transport of oxygen through hemoglobin has been studied by use of a membrane sandwich of hemoglobin, Teflon, and water. Transport is enhanced only when there is a hemoglobin-bound-02 gradient in the pigment. When passing through a fully oxygenated layer, the accelerated transport is carried by an increased diffusion gradient of oxygen pressure through the solvent. The results substantiate experimentally the diffusion gradients proposed by Zilversmit.

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