Cellular Origin of Hyaluronateprotein in the Human Synovial Membrane

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Science  15 Oct 1965:
Vol. 150, Issue 3694, pp. 353-355
DOI: 10.1126/science.150.3694.353


Bright fluorescent staining, which indicates the presence of hyaluronateprotein, was observed in the lining cells of the synovial membrane following application of rabbit antiserum to hyaluronateprotein and a fluorescein-labeled antiserum to rabbit γ-globulin. Staining was shown to be specific and due to antigenic determinants on or closely associated with the protein moiety of hyaluronateprotein.