Lithocholic Acid in Human-Blood Serum

Science  29 Oct 1965:
Vol. 150, Issue 3696, pp. 620-622
DOI: 10.1126/science.150.3696.620


Lithocholic acid was present in the serum of three patients with, jaundice and, in smaller amounts, in two healthy adults. This bile acid occurs naturally in human feces but induces cirrhosis of the liver when fed to a wide variety of experimental animals. The finding of lithocholic acid in blood is of interest because of its possible role in injuring human liver.