Selective Mitochondrial Damage by a Ruby Laser Microbeam: An Electron Microscopic Study

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Science  05 Nov 1965:
Vol. 150, Issue 3697, pp. 756-758
DOI: 10.1126/science.150.3697.756


A pulsed ruby laser microbeam produces changes in single living cells stained with a low concentration of Janus green B. Electron micrographs show that such alterations are the result of morphological damage sustained by and restricted to the mitochondria in the irradiated area.