Lymphoma Growth in vivo: Electronic Discrimination between Tumor and Stroma Cells

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Science  05 Nov 1965:
Vol. 150, Issue 3697, pp. 769-771
DOI: 10.1126/science.150.3697.769


Moloney lymphoma cells are larger than normal cells of mouse spleen, lymph-node, and thymus. Use of electronic cell-size anaylsis in conjunction with specific immunocytolysis permits difjerential counting of host and tumor cells. Increase of lymphoma cells occurs first in spleen and then in lymph nodes; in thymus it occurs only during the terminal stages of tumor growth.