Antibodies in Gastric Juice

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Science  10 Dec 1965:
Vol. 150, Issue 3702, pp. 1467-1469
DOI: 10.1126/science.150.3702.1467-a


The presence in gastric juice of specific antibody has been demonstrated. It is mainly an IgG antibody reacting with the cytoplasm of gastric cells; it has been detected in patients with atrophic gastritis, with or without pernicious anemia, whose serums contain antibodies to parietal-cell cytoplasm. Evidence is presented that associated circulating antibody to cytoplasm of thyroid acinar cell does not appear in the gastric juice.