Increased Activities of Glycogenolytic Enzymes in Liver after Splanchnic-Nerve Stimulation

See allHide authors and affiliations

Science  17 Dec 1965:
Vol. 150, Issue 3703, pp. 1607-1608
DOI: 10.1126/science.150.3703.1607


Electrical stimulation of the splanchnic nerve of rabbits caused a marked increase, within 30 seconds after the onset of stimulation, in liver-glycogen phosphorylase and glucose-6-phosphatase activities. The increased activity of liver phosphorylase after splanchnic-nerve stimulation was likewise observed in adrenalectomized and pancreatectomized rabbits. Glycogen content of the liver decreased only slightly after 5-minute stimulation.