Polymorphism of Lactate Dehydrogenase in Gelada Baboons

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Science  14 Jan 1966:
Vol. 151, Issue 3707, pp. 206-208
DOI: 10.1126/science.151.3707.206


In a group of 21 gelada baboons, three different lactate dehydrogenase patterns were observed after starch-gel electrophoresis of tissue extracts. The patterns indicate that a mutation has occurred in this population in the gene responsible for the A-subunit. The normal and variant homozygotes each contain five isozymes, those containing the A subunit having characteristically different electrophoretic mobilities. The heterozygote contains the expected 15 isozymes.