Hyperphagia in Ruminants Induced by a Depressant

Science  28 Jan 1966:
Vol. 151, Issue 3709, pp. 458-459
DOI: 10.1126/science.151.3709.458


Attempts at causing ventromedial hyperphagia in ruminants have been hitherto unsuccessful. In our experiments perfusion of the ventriculocisternal system with pentobarbital caused marked hyperphagia. This suggests that the ventromedial hypothalamic area is functioning in ruminants, probably as in monogastric animals, by inhibiting the lateral area.