Phenylalanine: Transplacental centrations in Rhesus Monkeys

See allHide authors and affiliations

Science  18 Feb 1966:
Vol. 151, Issue 3712, pp. 823-825
DOI: 10.1126/science.151.3712.823


Arbino acids are actively transported across the mammalian placenta, crncentrations in fetal blood being higher than those in the maternal circu-Elevated concentrations of phenylalanine were induced by dietarv means blood of pregnant rhesus monkeys, and the active transport mechanism vident at both normal and elevated concentrations. A normal placental may thus magnify a maternal biochemical abnormality and produce a profound disturbance in the fetus.