Interferon: Lack of Detectable Uptake by Cells

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Science  01 Apr 1966:
Vol. 152, Issue 3718, pp. 80-82
DOI: 10.1126/science.152.3718.80


No interferon, or at most a small fraction of that applied, is taken up by cells during the period of induction of antiviral activity. The lack of detectable adsorption was not influenced either by the concentration of interferon or the volume. The results were similar in both chicken and mouse systems.