Iodoinsulin Used To Determine Specific Activity of Iodine-131

See allHide authors and affiliations

Science  08 Apr 1966:
Vol. 152, Issue 3719, pp. 205-207
DOI: 10.1126/science.152.3719.205


Anodal mobility of iodoinsulin on starch-gel electrophoresis increases progressively as the number of iodine atoms substituted in the molecule increases. The iodine content of iodine-131 solutions is determined by comparison of autoradiographic patterns of insulin heavily labeled with iodine-131 and of insulins lightly labeled with iodine-131 and known quantities of iodine-127.