Tropomyosin Paracrystals Formed by Divalent Cations

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Science  06 May 1966:
Vol. 152, Issue 3723, pp. 794-796
DOI: 10.1126/science.152.3723.794


Rabbit tropomyosin exhibits a polymorphism dependent on divalent cations and pH. Above a critical divalent cation concentration fibers with a period of about 400 angstroms are formed. Below this concentration, and near the isoelectric point, lattices are formed. Implications for the morphology and function of striated and smooth muscle are discussed.