Virus-induced Murine Leukemia: Its Inhibition and Suppression by Serum Containing Erythropoietin

See allHide authors and affiliations

Science  20 May 1966:
Vol. 152, Issue 3725, pp. 1082-1083
DOI: 10.1126/science.152.3725.1082


Mice infected at 2 days of age with a virus that induces reticulum cell sarcoma and myeloerythroleukemia were treated with erythropoietin-containing serum obtained from rabbits that had been treated with acetylphenylhydrazine. A marked inhibition of tumor induction occurred, particularly in females, when treatment was begun early. Delayed treatment resulted in instances of regression of overt neoplasia.