Plasma Chromium after Glucose Administration

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Science  27 May 1966:
Vol. 152, Issue 3726, pp. 1243-1245
DOI: 10.1126/science.152.3726.1243


Sharp increases in the concentration of chromium in plasma were found in five subjects with normal glucose utilization after administration of glucose by mouth. This rise was not observed in two diabetics when glucose tolerance was impaired; however, it appeared when glucose tolerance was improved and when trace amounts of trivalent chromium were given as a dietary supple-ment. The source of chromium which became elevated was most likely an internal pool. Possibly there is a relation between chromium and insulin function.