Mammary Tumor Inhibition and Lung Adenoma Induction by Isonicotinic Acid Hydrazide

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Science  03 Jun 1966:
Vol. 152, Issue 3727, pp. 1376-1377
DOI: 10.1126/science.152.3727.1376


The occurrence of manomary adenocarcinonmas in C3H mice is largely inhibited by prolonged admninistration of 0.1 percent isonicotinic acid hydrazide in drinking water. At the same time that this compound produtced the inhibitory action, it also increased the incidence of pulmonary adenomas.