Electrophoretic Heterogeneity of the Polypeptide Chains of Human G-Myeloma Proteins

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Science  17 Jun 1966:
Vol. 152, Issue 3729, pp. 1628-1630
DOI: 10.1126/science.152.3729.1628


The light and heavy polypeptide chains derived from human Gmyeloma proteins are electrophoretically heterogeneous as judged by disc electrophoresis of the polypeptide chains in urea-acrylamide gels. Individual myeloma proteins contained as many as eight light-chain and nine heavy-chain components.