Reports

Actin: Volume Change on Transformation of G-Form to F-Form

Science  24 Jun 1966:
Vol. 152, Issue 3730, pp. 1756-1757
DOI: 10.1126/science.152.3730.1756

Abstract

The volume change occurring on polymerizing actin was measured by dilatometry. A large positive value of + 391 ml/mole was obtained for the volume change during the transformation of G- to F-actin. This large increase in volume could be interpreted as arising from the local change in the ordered water structure on the protein's surface at polymerizing sites.

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