Rat Mammary Gland RNA: Incorporation of C14-Formate and Effect of Hormones and 7,12-Dimethylbenz[alanthracene

Science  15 Jul 1966:
Vol. 153, Issue 3733, pp. 303-305
DOI: 10.1126/science.153.3733.303


In female rats, the incorporation of sodium C14-formate into mammary gland RNA decreases immediately after a singlefeeding of 20 milligrams of 7,12-dimethylbenz[a] anthracene. In males, there is a gradual increase in the incorporation. In castrated rats, the decrease or increase of C14-formate incorporation is dependent on the presence of estrogen or androgen, respectively.