Reports

Galactose Conversion to d-Xylulose: An Alternate Route of Galactose Metabolism

Science  29 Jul 1966:
Vol. 153, Issue 3735, pp. 549-551
DOI: 10.1126/science.153.3735.549

Abstract

Galactose dehydrogenase, a soluble enzyme of the mammalian liver, catalyzes the conversion of galactose to galactonic acid. This reaction, together with the subsequent formation of 3-ketogalactonic acid which can be decarboxylated to yield d-xylulose, is a newly discovered pathway for the metabolism of galactosee. This pathway may account for the oxidation of galactose observed in pathients with galactosemia.

Related Content