Glial Responses to Degenerating Cerebellar Cortico-nuclear Pathways in the Cat

Science  29 Jul 1966:
Vol. 153, Issue 3735, pp. 553-555
DOI: 10.1126/science.153.3735.553


Astrocytic changes in regions of long-term, cerebellar corticonuclear degeneration are characterized by large increases in cytoplasmic volume, as well as by formation of vacuoles and fibrils. Lipids are demonstrable in the vacuoles with oil red-O staining.