Plasma Replacement for in vitro Culture of Plasmodium klowlesi

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Science  02 Sep 1966:
Vol. 153, Issue 3740, pp. 1129-1130
DOI: 10.1126/science.153.3740.1129


Of six fractions of human plasma tested, only Cohn's fraction IV-4 was effective for the replacement of whole plasma from monkey (Macaca mulatta) for the in vitro culture of Plasmodium knowlesi. The effects observed on multiplication and morphology of parasites suggest a specific role of some substance or substances in fraction IV-4.