1,2- Dialkyl- 4(3H)- Quinazolinones in the Defensive Secretion of a Millipede ( Glomeris marginata)

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Science  21 Oct 1966:
Vol. 154, Issue 3747, pp. 390-391
DOI: 10.1126/science.154.3747.390


Two crystalline components isolated from the defensive secretion of the glomerid millipede, Glomeris marginata, are identified as 1- methyl- 2- ethyl- 4( 3H)- quinazolinone and 1,2- dimethyl- 4( 3H)- quinazolinone. These heterocyclic compounds bear a close structural resemblance to arborine, the chief alkaloid of the Indian medicinal plant, Glycomis arborea Correa.