Inherited Variations of Human Serum α1-Antitrypsin

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Science  21 Oct 1966:
Vol. 154, Issue 3747, pp. 407-408
DOI: 10.1126/science.154.3747.407


The normal serum α1-antitrypsin migrates as a three banded patternwhen separated electrophoretically in starch gel with a sodium acetateethylenediaminetetraacetic acid buffer of pH 4.95. The results obtained when certain inherited variants of the serum α1-antitrypsin are separated electrophoretically suggest that the previously described variations in the region preceding the albumin band represent inherited variations of the serum α1-antitrypsin.