Anticholinergic Blockade of Centrally Induced Thirst

See allHide authors and affiliations

Science  28 Oct 1966:
Vol. 154, Issue 3748, pp. 520-522
DOI: 10.1126/science.154.3748.520


A cholinergic antagonist applied to many of the limbic and diencephalic structures, cholinergic stimulation of which induces thirst, prevents drinking in response to cholinergic stimulation of other parts of the system. Thus, the elicitation of drinking after chemical stimulation of a particular site seems to be dependent on the functional state of other structures in the circuit.