Electrophoretic Heterogeneity of Mammalian Galactose Dehydrogenase

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Science  28 Oct 1966:
Vol. 154, Issue 3748, pp. 533-535
DOI: 10.1126/science.154.3748.533


Electrophoretically distinct forms of galactose dehydrogenase were demonstrated in various tissues of the rat. Phylogenetic comparisons revealed considerable variation with species in mammalian liver zymograms; virtually no activity was demonstrable in fish, pigeon, and frog liver. Ontogenetic studies of the rat revealed sequential appearance of liver isoenzymes.