Homoreactant: A Naturally Occurring Autoantibody in Rabbits

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Science  04 Nov 1966:
Vol. 154, Issue 3749, pp. 651-652
DOI: 10.1126/science.154.3749.651


Homoreactant, a factor found in the serum of every normal rabbit tested thus far, reacts specifically with buried antigenic determinants on the Fab-fragment of papain-digested autologous and homologous γG-globulin. It appears that rabbits normally produce naturally occurring autoantibodies.