Adrenalectomy and Coat Color in Deer Mice

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Science  09 Dec 1966:
Vol. 154, Issue 3754, pp. 1349-1350
DOI: 10.1126/science.154.3754.1349


Adrenalectomy in prairie deer mice is followed by a profound darkening of the fur which occurs with in 1 to 3 months. The phenomenon is most noticeable on the normally unpigmented ventral surfaces which turn dark gray or black. A possible mechanism for such hyperpigmentation would involve increased release of inelanocyte-stimulating hormones.