Leukocyte Mitosis: Suppression in vitro Associated with Acute Infectious Hepatitis

Science  06 Jan 1967:
Vol. 155, Issue 3758, pp. 80-81
DOI: 10.1126/science.155.3758.80


Inhibition of mitosis in vitro was observed in leukocytes from patients with acute infectious hepatitis. Similarly, in cultures of normal leukocytes, after the addition of small amounts of serum from patients with hepatitis, mitosis was suppressed. Althoutgh the incidence of mitosis became normal in leukocytes from convalescent patients, there were chromosomal abnormalities.