Erythrocyte Chimerism after Injection of Spleen Cells into Anemic Mice of the W-Series

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Science  06 Jan 1967:
Vol. 155, Issue 3758, pp. 90-91
DOI: 10.1126/science.155.3758.90


Anemic mice (WvWv) when injected at birth with a mixture of isologous (genotype Wvw) and homologous spleen cells, showed an improvement in their peripheral blood picture when adult. Red blood counts, red cell size, and electrophoresis of the hemoglobins indicated that, in some cases, the homologous tissue had become implanted and, in others, the isologous tissue was functioning.