Hexokinase Isoenzymes in Liver and Adipose Tissue of Man and Dog

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Science  13 Jan 1967:
Vol. 155, Issue 3759, pp. 205-207
DOI: 10.1126/science.155.3759.205


A hexokinase, with a low Michaelis constant, not previously described, has been found in extracts of human and dog liver but not of rat liver. Earlier reports are contradicted in that glucokinase occurs in extracts of liver from well-nourished humans and dogs; it is absent, or almost so, during states of poor nutrition.