Photoinduced DNA-Protein Cross-Links and Bacterial Killing: A Correlation at Low Temperatures

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Science  24 Feb 1967:
Vol. 155, Issue 3765, pp. 1024-1026
DOI: 10.1126/science.155.3765.1024


The increased sensitivity of Escherichia coli to killing by ultraviolet irradiation when frozen and the variation in this sensitivity as a function of the temperature during irradiation have been correlated with changes in the amount of DNA that was cross-linked to protein by ultraviolet light. These variations in sensitivity to killing do not correlate with the production of thymine dimers.