Loss of Thymus-Distinctive Serological Characteristics in Mice under Certain Conditions

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Science  03 Mar 1967:
Vol. 155, Issue 3766, pp. 1114-1116
DOI: 10.1126/science.155.3766.1114


The serological properties of thymus cells of inbred mice bearing Ehrlich ascites tumors and treated with cortisol were investigated. Thymusdistinctive antigenicity and sensitivity to the cytotoxic effect of guinea pig serum and rabbit serum were significantly decreased, without change in reactivity to H-2 isoantibodies.