Mammalian X-Chromosomes: Change in Patterns of DNA Replication during Embryogenesis

See allHide authors and affiliations

Science  03 Mar 1967:
Vol. 155, Issue 3766, pp. 1120-1121
DOI: 10.1126/science.155.3766.1120


One arm of both X-chromosomes in female eight-cell embryos of the golden hamster replicates late in the period of DNA synthesis. Midgestation embryos and adult fibroblasts show an increase in late-replicating DNA. Here, one X-chromosome is labeled in one arm; the other is labeled throughout.