Sulfur Mustard and X-Rays: Differences in Expression of Lethal Damage

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Science  24 Mar 1967:
Vol. 155, Issue 3769, pp. 1561-1563
DOI: 10.1126/science.155.3769.1561


Before or after treatment with sulfur mustard, simple changes in the incubation conditions of cultured Chinese hamster cells lead to changes as great as a factor of 6 in survival-curve slopes. With x-ray treatment, changes are similar but much smaller in magnitude. These results suggest that the modes of action of these agents are not entirely the same.