Genetic Control of Lactate Dehydrogenase Formation in the Hagfish Eptatretus stoutii

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Science  07 Apr 1967:
Vol. 156, Issue 3771, pp. 96-98
DOI: 10.1126/science.156.3771.96


The isozyme patterns of lactate dehydrogenases of various tissues were studied on 51 hagfish by starch-gel electrophoresis. Nine lactate dehydrogenase phenotypes were encountered, suggesting the coexistence of two alleles at each of the two separate gene loci. There apparently was no interaction between the products of these two separate loci. Even the products of two alleles at the same locus were apparently incapable of forming hybrid molecules, an indication of the possible monomeric nature of each lactate dehydrogenase molecule.