Gastrin Antibodies: Induction, Demonstration, and Specificity

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Science  21 Apr 1967:
Vol. 156, Issue 3773, pp. 391-392
DOI: 10.1126/science.156.3773.391


Antibodies to the antral hormone gastrin have been induced in the rabbit and detected by passive hemagglutination. Specificity of the antibody, as determined by three methods, is directed to gastrins I and II, gastrin pentapeptide, and gastrin tetrapeptide, as well as to the stage-1 gastrin used for immunization.